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Mmi1

There is 1 paper on Mmi1 in aging research: none in people yet, 1 in cells.

Gene

1 paper studies it3 findings

Taxon

See all 1 papers on Mmi1

At a glance

The findings reach worms or flies, none yet in people. 1 lab in 1 country.

1 of its findings points the other way.

Worms or flies: a single group. Cells, mice and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Against: findings that point the other way from most findings on the same outcome.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • 1 finding against
  • Funders: Grantová Agentura České Republiky and 3 more
  • Cells1

Effects

2

Autophagy

no changein yeast cells1downin yeast cells1

1 study

  1. Mmi1 showed no clear effect on autophagy in yeast cells (basal and nitrogen starvation-induced).

    “Our results demonstrate that Mmi1 does not affect basal or nitrogen starvation-induced autophagy.”

    Cellsbasal and nitrogen starvation-induced

    Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase

    Cells

  2. Mmi1 inhibits autophagy in yeast cells (rapamycin-induced; post-diauxic growth phase; shown by mmi1Δ deletion).

    “an increased rapamycin-induced autophagy is detected in mmi1Δ strain when the cells enter the post-diauxic growth phase”

    Cellsrapamycin-induced; post-diauxic growth phase; shown by mmi1Δ deletion

    Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase

    Cells

More on Autophagy

Oxidative stress and ROS signaling

upin yeast cells1

1 study

  1. Mmi1 increases oxidative stress and ROS signaling in yeast cells (post-diauxic growth phase; shown by mmi1Δ deletion) (significantly lower ROS in mmi1Δ versus WT).

    “the mmi1Δ cells exhibit significantly lower amounts of reactive oxygen species (ROS) in the post-diauxic growth phase compared to WT cells”

    Cellspost-diauxic growth phase; shown by mmi1Δ deletion

    Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase

    Cells

More on Oxidative stress and ROS signaling

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