There are 2 papers on mmcm-1 in aging research: none in people yet, 2 in animals. The newest story, Nov 2, 2026: “Worms lacking a regulatory protein lived longer on certain diets”.
1 new paper in 30 daysSee all 2
Lifespan
is required forin worms1
mmcm-1 is required for lifespan in rict-1 mutants on B12-rich bacterial diets.
“These phenotypic adaptations require two B12-dependent enzymes: methionine synthase (METR-1), functioning in the folate-methionine cycle (Met-C), and methylmalonyl-CoA mutase (MMCM-1)”
Model organismsin rict-1 mutants on B12-rich bacterial diets
bioRxiv : the preprint server for biologyPreprint
Worm experiments traced the lifespan benefit to vitamin B12-dependent enzymes and a process that removes mitochondria, the cell’s energy-producing structures.Worm experiments traced the lifespan benefit to vitamin B12-dependent enzymes and a process that removes mitochondria, the cell’s energy-producing structures.