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MIR675

There are 2 papers on MIR675 in aging research: 1 observational study in people, 1 review.

Gene

2 papers study it2 findings

HGNCNCBI GeneTaxon

See all 2

“In larger cohorts, miR-675 and its host gene (H19) were higher in patients with a low FFMI and strength.”
Increased expression of H19/miR-675 is associated with a low fat-free mass index in patients with COPDJournal of cachexia, sarcopenia and muscle2016doi:10.1002/jcsm.12078

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Biotechnology and Biological Sciences Research Council and 5 more
  • Humans1

Effects

1

Myoblast proliferation

downin cells1

1 study

  1. MIR675 inhibits myoblast proliferation in cells.

    “In vitro, miR-675 inhibited myoblast proliferation”

    Cellsmyoblast

    Increased expression of H19/miR-675 is associated with a low fat-free mass index in patients with COPD

    Journal of cachexia, sarcopenia and muscle

Associations

1

Fat-free mass index

downin humans1

1 study

  1. MIR675 is associated with fat-free mass index in humans (COPD).

    “In larger cohorts, miR-675 and its host gene (H19) were higher in patients with a low FFMI and strength.”

    HumansCOPDquadriceps muscle

    Increased expression of H19/miR-675 is associated with a low fat-free mass index in patients with COPD

    Journal of cachexia, sarcopenia and muscle

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