MIAT
None of its findings points the other way.
- 3 independent labs in 3 countries
- Funders: Amgen and others
- 1 of 3 findings with company ties
- Human trial1
- Humans2
- Animals2
Interventions
1High-intensity interval training
no changein humans1
1 study
High-intensity interval training
no changein humans1
High-intensity interval training has no effect on MIAT in humans.
“Notably, no significant main effect for time was found for the MIAT relative expression after the 8 weeks of treatment compared to baseline (0 weeks).”
Human trialafter 8 weeks of treatment compared to baseline8 weeksfemalesn = 48
Preventive nutrition and food science
Associations
2Type 2 diabetes
upin humans1
1 study
Type 2 diabetes
upin humans1
MIAT is associated with type 2 diabetes in humans.
“Four lncRNAs (ANRIL, MIAT, RNCR3, and PLUTO) were associated with incident type 2 diabetes”
Humansindividuals without diabetes7.5 yearsn = 296
Diabetes care
Erbb4 splice isoform expression
mixedin mice1
1 study
Erbb4 splice isoform expression
mixedin mice1
MIAT is associated with Erbb4 splice isoform expression in mice.
“find a developmental switch in ErbB4 splice isoform expression potentially mediated through coregulation of the lncRNA Miat expression.”
Animalsprefrontal cortex
Temporal Dynamics of the Neuregulin-ErbB Network in the Murine Prefrontal Cortex across the Lifespan
Cerebral cortex (New York, N.Y. : 1991)
Latest
1 paper in 12 monthsJournal of Molecular Neuroscience
Single Nucleotide Polymorphisms in Stroke: Evidence Across Susceptibility, Prognosis, and Recurrence; A Systematic Review
Systematic review of observational studiesStroke
Clinical Epigenetics
DNA methylation in peripheral blood is associated with renal aging and renal function decline: a national community study
Cohort study of 1,587 peopleDNA methylation
Preventive Nutrition and Food Science
Influence of 8 Weeks of Tabata High-Intensity Interval Training and Nanocurcumin Supplementation on Inflammation and Cardiorespiratory Health among Overweight Elderly Women
Randomized trial in 48 peopleHigh-intensity interval training
GeroScience
Divergent regulation of lncRNA expression by ischemia in adult and aging mice
Experiments in miceMechanisms
Cerebral Cortex
Temporal Dynamics of the Neuregulin-ErbB Network in the Murine Prefrontal Cortex across the Lifespan
Experiments in miceMechanisms