MCRS1

1. MCRS1 increases tumor growth in mice.

   “in vivo experiments using an orthotopic BC model in C57BL/6 mice demonstrated significantly reduced tumor growth.”

   Animalsknockdown of Mcrs1mammary gland

   Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression

   International journal of surgery (London, England)·20 Jan 2026

1. MCRS1 increases cell proliferation in mouse cells.

   “genetic knockdown of Mcrs1 profoundly suppressed BC cell proliferation and invasion in vitro”

   Cellsknockdown of Mcrs1

   Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression

   International journal of surgery (London, England)·20 Jan 2026

1. MCRS1 raises the risk of breast cancer in silico.

   “Mendelian randomization established MCRS1 as the sole causal risk factor for BC among these candidates.”

   In silico

   Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression

   International journal of surgery (London, England)·20 Jan 2026

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