LTBP2

  • 1 lab
  • Humans2

Associations

1

Primary open-angle glaucoma

upin humans1OR 4.14

1 study
  1. LTBP2 raises the risk of primary open-angle glaucoma in humans (OR 4.14, 95% CI 2.73 - 6.28).

    Humansheterozygous loss-of-function variantsn = 450,000

    LTBP2 gene variants linked to adult glaucoma risk

    Genetics in medicine : official journal of the American College of Medical Genetics8 Oct 2026

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Genetics in Medicine

LTBP2 gene variants linked to adult glaucoma risk

Carrying one faulty copy of the LTBP2 gene was linked to a fourfold higher risk of adult glaucoma and diagnosis eight years earlier.Carrying one faulty copy of the LTBP2 gene was linked to a fourfold higher risk of adult glaucoma and diagnosis eight years earlier.

Cohort study of 450,000 peopleEye