Major adverse cardiac and cerebrovascular events

1. Trimethylamine n-oxide is associated with major adverse cardiac and cerebrovascular events in humans (HR 1.10, 95% CI 1.03-1.17).

   Humansin 34 cohort studies after correction for publication bias

   Trimethylamine N-oxide and major adverse cardiac and cerebrovascular events: results of umbrella review and meta-analysis · Nutrition & metabolism · 23 Sep 2026

Trimethylamine n-oxide →

1. Alcohol use disorder predicts major adverse cardiac and cerebrovascular events in humans.

   Humansin trauma-exposed adults

   Post-traumatic Psychopathology and Cardiovascular Risk: A Danish Case-Control Study of Sex-Specific Associations · Journal of the American Heart Association · 2 Sep 2026

Alcohol use disorder →

1. Psychiatric disorder raises the risk of major adverse cardiac and cerebrovascular events in humans.

   Humansfollowing trauma

   Post-traumatic Psychopathology and Cardiovascular Risk: A Danish Case-Control Study of Sex-Specific Associations · Journal of the American Heart Association · 2 Sep 2026

Psychiatric disorder →