LIPC

1. LIPC lowers the risk of chronic kidney disease in humans (OR 0.83 [95% CI 0.74 to 0.92]).

   Humansin African ancestry

   The Role of Angiopoietin-Like Proteins 3 and 4 and Their Target Lipases in CKD: A Drug-Target Mendelian Randomization Study · American journal of kidney diseases : the official journal of the National Kidney Foundation · 22 Sep 2026

Chronic kidney disease →

1. LIPC is associated with dyslipidemia in humans (P = 9.42 × 10-51).

   Humansmulti-trait analysis of lipid traits in African-ancestry populationsn = 34,039

   Pleiotropy and eQTL analysis identify shared genetic architecture of lipid traits in African-ancestry populations · Human molecular genetics · 11 Sep 2026

Dyslipidemia →