Hbegf
GeneRattus norvegicus1 paper2 findingsNCBI Gene 25433Taxon 10116
- Animals1
Interventions
1Cinaciguat
upin rats1
1 study
Cinaciguat
upin rats1
Cinaciguat increases Hbegf in rats.
Animalsliver sinusoidal endothelial cell
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026
Effects
1Altered intercellular communication
mediatesin rat cells1
1 study
Altered intercellular communication
mediatesin rat cells1
Hbegf mediates altered intercellular communication in rat cells.
CellsLSEC-hepatocyte interaction
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026
Latest
1Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats
Cinaciguat reversed endothelial defenestration and restored paracrine signaling that enables rat hepatocytes to clear circulating lipids and amyloid-beta.
The Journal of biological chemistry · de Leve SJ et al.