GRIK5

1 paper1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funder: National Institute on Aging

Animals1

Upstream

1

PSEN2

downin mice1

1 study

PSEN2 decreases GRIK5 in mice.
“GluK5 expression was significantly reduced in aged seizure-naïve PSEN2 KO versus WT mice”
Animalsin aged seizure-naïve micehippocampus
Loss of presenilin 2 function age-dependently increases susceptibility to kainate-induced acute seizures and blunts hippocampal kainate-type glutamate receptor expression
Experimental neurology9 Dec 2025

Latest

1 in 12 months

Experimental Neurology12 Dec

Loss of presenilin 2 function age-dependently increases susceptibility to kainate-induced acute seizures and blunts hippocampal kainate-type glutamate receptor expression

Experiments in miceMechanisms