eri-1

There are 4 papers on eri-1 in aging research: none in people yet, 4 in animals. The newest story, Oct 30, 2026: “Mother’s age shapes offspring avoidance behavior in worms”.

Gene

4 papers study it5 findings

NCBI GeneTaxon

1 new paper in 30 daysSee all 4

None of its findings points the other way.

  • 3 independent labs in 2 countries
  • Funders: National Institutes of Health and 5 more
  • Model organisms4

Effects

3

mir-8207

downin worms1

1 study
  1. eri-1 inhibits mir-8207 in worms.

    “ERI-1 promotes expression of the neuropeptide gene flp-26 by repressing mir-8207”

    Model organismsAVH interneuron

    Mother’s age shapes offspring avoidance behavior in worms

    Genes & development

More on mir-8207

FLP-26 expression

upin worms1

1 study
  1. eri-1 increases FLP-26 expression in worms.

    “ERI-1 promotes expression of the neuropeptide gene flp-26 by repressing mir-8207”

    Model organismsAVH interneuron

    Mother’s age shapes offspring avoidance behavior in worms

    Genes & development

More on FLP-26 expression

Lifespan

is required forin worms1

1 study
  1. eri-1 is required for lifespan in worms (reserpine-induced lifespan extension).

    “In the absence of eri-1, RMLE is shortened.”

    Model organismsreserpine-induced lifespan extension

    Reserpine requires the D2-type receptor, dop-3, and the exoribonuclease, eri-1, to extend the lifespan in C. elegans

    Journal of biosciences

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 12 papers in 12 months
Genes & Development

Mother’s age shapes offspring avoidance behavior in worms

Experiments in worms linked older mothers to offspring with weaker nerve-cell responses and less avoidance of a chemical social signal.Experiments in worms linked older mothers to offspring with weaker nerve-cell responses and less avoidance of a chemical social signal.

Worm studyMechanisms