DTX2

1 paper5 findings

Ovarian DTX2 decreases with ageing in a mouse study. In human KGN cells under H2O2-induced damage, DTX2 inhibits apoptosis and the DNA damage response; knockdown experiments link DTX2 to increased TERT and reduced telomere shortening. All five findings come from one lab and name the China Postdoctoral Science Foundation as funder.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.

1 lab in 1 country

Funder: China Postdoctoral Science Foundation

Cells1

Effects

Apoptosis

downin human cells1

1 study

DTX2 inhibits apoptosis in human cells.
Cellsunder H2O2-induced DNA damage conditions in KGN cellsgranulosa cell
A Novel Role of DELTEX2 in Maintaining Genomic Stability of Granulosa Cells During Ovarian Aging
FASEB journal : official publication of the Federation of American Societies for Experimental Biology24 Aug 2026

Upstream

Ovarian aging

downin mice1

1 study

Ovarian aging decreases DTX2 in mice.
Animalsaged miceovary
A Novel Role of DELTEX2 in Maintaining Genomic Stability of Granulosa Cells During Ovarian Aging
FASEB journal : official publication of the Federation of American Societies for Experimental Biology24 Aug 2026

Latest

1 in 12 months

FASEB Journal24 Aug

A Novel Role of DELTEX2 in Maintaining Genomic Stability of Granulosa Cells During Ovarian Aging

Experiments in human cellsReproductive system

Paper

DTX2

Effects

Upstream

Latest

A Novel Role of DELTEX2 in Maintaining Genomic Stability of Granulosa Cells During Ovarian Aging

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