DAP3
- 1 lab in 1 country
- Funders: Fundamental Research Funds for the Central Universities and 3 more
- Animals1
Effects
3Mitochondrial complex I activity
upin human cells1
1 study
Mitochondrial complex I activity
upin human cells1
DAP3 increases mitochondrial complex I activity in human cells.
“DAP3 can increase mitochondrial complex I activity in HCC cells by regulating the translation and expression of MT-ND5.”
Cellsthrough regulation of MT-ND5 translation and expressionhepatocellular carcinoma cell
Cell death & disease29 Jul 2024
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
DAP3 decreases cellular senescence in human cells.
“by increasing mitochondrial respiration, inducing the epithelial-mesenchymal transition (EMT), and slowing cellular senescence.”
Cellshepatocellular carcinomahepatocellular carcinoma cell
Cell death & disease29 Jul 2024
HCC cell proliferation, migration, and invasion
upin human cells1
1 study
HCC cell proliferation, migration, and invasion
upin human cells1
DAP3 increases HCC cell proliferation, migration, and invasion in human cells.
“DAP3 can promote the proliferation, migration, and invasion of HCC cells in vitro and in vivo”
Cellshepatocellular carcinomahepatocellular carcinoma cell
Cell death & disease29 Jul 2024
Associations
1Patient survival
downin humans1
1 study
Patient survival
downin humans1
DAP3 is associated with patient survival in humans.
“the DAP3 expression in HCC samples is inversely correlated with patient survival.”
Humanshepatocellular carcinomahepatocellular carcinoma sample
Cell death & disease29 Jul 2024