CSF YWHAG:NPTX2

1. CSF YWHAG:NPTX2 predicts symptomatic conversion in humans (1.7-fold).

   Humanspresymptomatic familial FTLD

   Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration · bioRxiv · 31 Aug 2026 · Preprint

1. CSF YWHAG:NPTX2 is associated with disease severity in humans.

   Humanssporadic and familial FTLD (C9orf72, GRN, or MAPT mutations)csf

   Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration · bioRxiv · 31 Aug 2026 · Preprint

1. Frontotemporal lobar degeneration is associated with CSF YWHAG:NPTX2 in humans.

   Humanssporadic and familial FTLD, AD, and dementia with Lewy bodiescsf

   Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration · bioRxiv · 31 Aug 2026 · Preprint

Frontotemporal lobar degeneration →