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ATN1

Gene

2 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of General Medical Sciences and 2 more
  • Model organisms2

Effects

2

Motility

downin flies2

2 studies

  1. ATN1 impairs motility in flies.

    “Fly motility, longevity and internal structures are negatively impacted by pathogenic ATN1.”

    Model organismspathogenic ATN1 (Q88) expression

    Insights into dentatorubral-pallidoluysian atrophy from a new Drosophila model of disease

    Neurobiology of disease5 Feb 2025

  2. ATN1 impairs motility in flies.

    “Fly motility, longevity and internal structures are negatively impacted by pathogenic ATN1.”

    Model organismsexpression of full-length human ATN1 with Q88 repeat

    Insights into Dentatorubral-Pallidoluysian Atrophy from a new Drosophila model of disease

    bioRxiv : the preprint server for biology10 Dec 2024Preprint

Lifespan

downin flies2

2 studies

  1. ATN1 shortens lifespan in flies.

    “Fly motility, longevity and internal structures are negatively impacted by pathogenic ATN1.”

    Model organismspathogenic ATN1 (Q88) expression

    Insights into dentatorubral-pallidoluysian atrophy from a new Drosophila model of disease

    Neurobiology of disease5 Feb 2025

  2. ATN1 shortens lifespan in flies.

    “Fly motility, longevity and internal structures are negatively impacted by pathogenic ATN1.”

    Model organismsexpression of full-length human ATN1 with Q88 repeat

    Insights into Dentatorubral-Pallidoluysian Atrophy from a new Drosophila model of disease

    bioRxiv : the preprint server for biology10 Dec 2024Preprint

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