Tissue dysfunction

1 paper

Animals1

Latest

33 in 12 months

Journal of Obesity & Metabolic Syndrome8 Oct

Advantages and Critical Reappraisal of New Clinical Obesity Definition Proposed by Lancet Commission

Ageing Research Reviews8 Oct

Nanoparticle-based senolytic and senomorphic therapies for healthy aging: design principles, translational evidence, and challenges

ReviewSenolytics

Biosensors8 Oct

Hybrid Multi-Biorecognition Laser-Scribed Graphene Platform for Electrochemical Detection of Insulin Resistance Biomarkers

Food Chemistry1 Oct

Artificial intelligence and in silico discovery of senolytic and senescence-associated food peptides

ReviewSenolytics

bioRxiv30 Sep

Blood and facial photos track organ aging and senescence scores in humans

Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.

Preprint: cohort study in peopleBiomarkers

Advanced Science30 Sep

Long-term human skin platform models chronic inflammation and senolytic treatments

The culture platform maintained native tissue architecture for four weeks, revealing treatment effects on aged donor tissue that emerged only after prolonged exposure.The culture platform maintained native tissue architecture for four weeks, revealing treatment effects on aged donor tissue that emerged only after prolonged exposure.

Experiments in human cellsInflammation

Nutrients28 Sep

Effects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review

ReviewCardiometabolic disease

Nature Cardiovascular Research24 Sep

Vascular aging as a driver of organ dysfunction and systemic aging

ReviewMechanisms

FASEB Journal23 Sep

Integrative Multi-Omics and Machine Learning Reveal Senescent Fibroblast-Associated ADAMTS2 as a Critical Indicator of Intestinal Inflammation in IBD

Experiments in human cellsCellular senescence

The Journal of Nutrition19 Sep

Schisandra chinensis Modulates Cellular Senescence through Integrated Regulation of Redox, Mitochondrial, and Inflammatory Homeostasis

ReviewInterventions