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Substance misuse

Disease

2 papers2 findings

  • Humans2

Associations

1

Cultural engagement

downin humans2HR 0.75

2 studies

  1. Cultural engagement is associated with substance misuse in humans (HR 0.75, 95% CI 0.59–0.95).

    “substance misuse (HR, 0.75; 95% CI, 0.59-0.95; FDR-adjusted P = .04)”

    HumansIncident hospital-treated disorders; fully adjusted analysisReceptive arts activitiesEvery few months up to monthly or moreUp to 20 yearsn = 8,274

    Cultural engagement linked to fewer mental disorders in older adults

    JAMA network open1 Oct 2026

  2. Cultural engagement lowers the risk of substance misuse in humans (HR 0.75, 95% CI 0.59-0.95).

    “substance misuse (0.75, 0.59-0.95, P FDR =0.040)”

    Humansup to 20 yearsn = 8,274

    Cultural engagement and mental disorders: A prospective negative control analysis of the English Longitudinal Study of Ageing with linked Hospital Episode Statistics

    medRxiv8 Jun 2026Preprint

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JAMA Network Open

Cultural engagement linked to fewer mental disorders in older adults

Frequent cultural engagement was linked to lower relative risk of hospital-treated mental disorders (hazard ratio 0.71), though the abstract did not specify the…Frequent cultural engagement was linked to lower relative risk of hospital-treated mental disorders (hazard ratio 0.71), though the abstract did not specify the comparison group.

Cohort study of 8,274 older adults, up to 20 years, against the never engaged groupMental disorders

Limit: Residual confounding may remain from unmeasured personality traits or early-life exposures

Paper

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