AgingResearch.NewsJoin free

Subclinical left ventricular dysfunction

There are 6 papers on subclinical left ventricular dysfunction in aging research: 6 observational studies in people. The newest story, Nov 7, 2026: “Gene variant linked to heart changes without heart failure”.

Disease

6 papers study it7 more mention it5 findings

5 new papers in 30 daysSee all 13 papers on subclinical left ventricular dysfunction

“ROC analysis showed robust diagnostic ability with an AUC of 0.86 (95% CI: 0.82-0.89).”
Artificial intelligence-enhanced electrocardiography for identifying subclinical left ventricular dysfunction in hypertensive individuals: a comprehensive clinical evaluationFrontiers in cardiovascular medicine2026doi:10.3389/fcvm.2026.1761335
  • Humans6

Associations

4

AI-ECG probability score

upin humans1OR 1.12

1 study

  1. AI-ECG probability score is associated with subclinical left ventricular dysfunction in hypertensive adults (adjusted OR 1.12 per 0.1 increase, 95% CI 1.07-1.18, p < 0.001).

    “the AI-ECG probability score remained independently associated with subclinical LV dysfunction (adjusted OR 1.12 per 0.1 increase, 95% CI 1.07-1.18; p < 0.001).”

    Humansin hypertensive adultsn = 348

    Artificial intelligence-enhanced electrocardiography for identifying subclinical left ventricular dysfunction in hypertensive individuals: a comprehensive clinical evaluation

    Frontiers in cardiovascular medicine

  2. AI-ECG probability score predicts subclinical left ventricular dysfunction in hypertensive adults (AUC 0.86, 95% CI 0.82-0.89).

    “ROC analysis showed robust diagnostic ability with an AUC of 0.86 (95% CI: 0.82-0.89).”

    Humansin hypertensive adultsn = 348

    Artificial intelligence-enhanced electrocardiography for identifying subclinical left ventricular dysfunction in hypertensive individuals: a comprehensive clinical evaluation

    Frontiers in cardiovascular medicine

More on AI-ECG probability score

Jointly high Fibrosis-4 index and triglyceride-glucose index

upin humans1OR 7.58

1 study

  1. Jointly high Fibrosis-4 index and triglyceride-glucose index is associated with subclinical left ventricular dysfunction in humans (type 2 diabetes mellitus; Fibrosis-4 index ≥1.3 and triglyceride-glucose index ≥9.03) (OR 7.58).

    “patients with both high Fib-4 (≥1.3) and high TyG (≥9.03) had the greatest SLVD risk (OR = 7.58)”

    Humanstype 2 diabetes mellitus; Fibrosis-4 index ≥1.3 and triglyceride-glucose index ≥9.03left ventricle

    TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross-sectional study

    Frontiers in endocrinology

More on Jointly high Fibrosis-4 index and triglyceride-glucose index

Triglyceride-glucose index

upin humans1OR 2.73

1 study

  1. Triglyceride-glucose index is associated with subclinical left ventricular dysfunction in humans (type 2 diabetes mellitus) (Adjusted OR 2.73, 95% CI 1.48–5.03).

    “TyG independently predicted SLVD (adjusted OR = 2.73, 95% CI: 1.48-5.03).”

    Humanstype 2 diabetes mellitusleft ventriclen = 270

    TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross-sectional study

    Frontiers in endocrinology

More on Triglyceride-glucose index

Metabolic dysfunction-associated fatty liver disease

upin humans1OR 3.21

1 study

  1. Metabolic dysfunction-associated fatty liver disease is associated with subclinical left ventricular dysfunction in humans (type 2 diabetes mellitus; compared with patients without MAFLD) (Adjusted OR 3.21, 95% CI 1.64–6.29).

    “MAFLD independently predicted SLVD (adjusted OR = 3.21, 95% CI: 1.64-6.29).”

    Humanstype 2 diabetes mellitus; compared with patients without MAFLDleft ventriclen = 270

    TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross-sectional study

    Frontiers in endocrinology

More on Metabolic dysfunction-associated fatty liver disease

Latest

Dec 2025: 0Jan 2026: 2Feb 2026: 2Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 1Sep 2026: 0Oct 2026: 3Nov 2026: 212 papers in 12 months
AHA Scientific Sessions 2026 Abstract

Gene variant linked to heart changes without heart failure

Compared with noncarriers, people with one copy had 2.09 times the odds of reduced heart-pumping function; those with two copies had 11.03 times the odds.Compared with noncarriers, people with one copy had 2.09 times the odds of reduced heart-pumping function; those with two copies had 11.03 times the odds.

Genetic association · 14,508 peopleBiomarkers
Paper

See all 13 papers on subclinical left ventricular dysfunction

Related