There is 1 paper on stone formation in aging research: none in people yet, 1 in animals.
1 paper studies it14 more mention it2 findings
2 new papers in 30 daysSee all 15 papers on stone formation
- Model organisms1
Upstream
2bnl
upin flies1
1 study
bnl
upin flies1
bnl increases stone formation in flies (shown by genetic overexpression in tubules).
“genetic overexpression of the fly FGF branchless (bnl) in the tubules induces expression of MFS2 and increases Malpighian tubule stones”
Model organismsshown by genetic overexpression in tubulesMalpighian tubule
Scientific reports
Mfs2
upin flies1
1 study
Mfs2
upin flies1
Mfs2 increases stone formation in flies (shown by RNAi knockdown on high Pi medium).
“RNAi-mediated knockdown of MFS2 increases blood (hemolymph) Pi and decreases formation of Malpighian tubule stones in flies cultured on high Pi medium.”
Model organismsshown by RNAi knockdown on high Pi mediumMalpighian tubule
Scientific reports
Latest
5 papers in 12 monthsScientific Reports
Endocrine regulation of MFS2 by branchless controls phosphate excretion and stone formation in Drosophila renal tubules
Experiments in fliesKidney
Frontiers in Endocrinology
Accelerated Biological Aging and Ultrasonography-Detected Nephrolithiasis Burden: A Two-Center Cross-Sectional Study
Accepted, not yet published: cross-sectional study of 2,689 peoplePhenoAge
Central European Journal of Urology
Glucagon-like peptide-1 receptor agonists, weight loss, and urolithiasis: what urologists should know
ReviewGLP-1 receptor agonists
Frontiers in Endocrinology
Longitudinal biological aging trajectories and incident urolithiasis: a causal mediation analysis role of metabolic dysfunction in a large Chinese cohort
Cohort study in peopleBiomarkers
Antioxidants & Redox Signaling
L-Ergothioneine Attenuates Nephrolithiasis by Modulating Redox Signaling and Mitochondrial Function in Cystine and Calcium Oxalate Models
Experiments in miceNephrolithiasis
Frontiers in Medicine
Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study
Cross-sectional study of 14,880 peopleNephrolithiasis
Current Osteoporosis Reports
Between a Rock and a Short Place-The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan
ReviewMechanisms