Spinal kyphosis
Disease1 paper1 finding
- Animals1
Upstream
1TP53
downin mice1
1 study
TP53
downin mice1
TP53 decreases spinal kyphosis in mice.
“Δ133p53α also mitigated spinal kyphosis and led to a modest increase in median lifespan.”
Animalstransgenic expression in a mouse model of Hutchinson-Gilford progeria syndromeΔ133p53α isoform
Human protein variant eased signs of progeria in mice · NPJ aging · 7 Oct 2026
Latest
1NPJ AgingAnimals
Human protein variant eased signs of progeria in mice
An animal experiment in genetically engineered mice found that the variant prevented characteristic tissue changes and modestly increased median…An animal experiment in genetically engineered mice found that the variant prevented characteristic tissue changes and modestly increased median lifespan.