SFR-defined hyposalivation

1. Xerogenic medications are associated with SFR-defined hyposalivation in humans (OR = 1.63; 95% CI, 1.12–2.36).

   “High-confidence xerogenic medication-class count was independently associated with SFR-defined hyposalivation (OR = 1.63; 95% CI, 1.12-2.36; p = 0.010).”

   Humansadjusted modelssalivahigh-confidence xerogenic medication-class countn = 850

   Xerogenic medications and clinical markers of salivary hypofunction

   Clinical oral investigations·13 Oct 2026

More on Xerogenic medications

1. Older age is associated with SFR-defined hyposalivation in humans (OR = 5.47; 95% CI, 1.44–20.78).

   “higher odds of SFR-defined hyposalivation (OR = 5.47; 95% CI, 1.44-20.78; p = 0.013)”

   Humansadjusted modelssalivan = 850

   Xerogenic medications and clinical markers of salivary hypofunction

   Clinical oral investigations·13 Oct 2026