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Pseudoxanthoma elasticum

Disease

2 papers study it2 more mention it3 findings

MeSH

  • Animals1
  • Cells1

Effects

3

Telomere length

upin human cells1

1 study

  1. Pseudoxanthoma elasticum increases telomere length in human cells.

    “The determination of the relative telomere length showed significantly longer telomeres for PXE fibroblasts compared to controls when cultivated in 10% FCS.”

    Cellscultivated in 10% FCS

    The Consideration of Pseudoxanthoma Elasticum as a Progeria Syndrome

    Frontiers in bioscience (Landmark edition)

More on Telomere length

FNTA

upin human cells1

1 study

  1. Pseudoxanthoma elasticum increases FNTA in human cells.

    “The gene expression of progerin and farnesyltransferase showed a significant increase in PXE fibroblasts when cultivated in 10% fetal calf serum (FCS) compared to controls.”

    Cellscultivated in 10% fetal calf serum (FCS)

    The Consideration of Pseudoxanthoma Elasticum as a Progeria Syndrome

    Frontiers in bioscience (Landmark edition)

More on FNTA

LMNA

downin human cells1

1 study

  1. Pseudoxanthoma elasticum decreases LMNA in human cells.

    “We could show a significant decrease of lamin A and C gene expression in PXE fibroblasts under nutrient depletion compared to controls.”

    Cellsunder nutrient depletion

    The Consideration of Pseudoxanthoma Elasticum as a Progeria Syndrome

    Frontiers in bioscience (Landmark edition)

More on LMNA

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