Prevalent dementia

Disease

1 paper2 findings

Humans1

Associations

High PCA-derived retinal reflectance score with GC-IPL thinning

upin humans1OR 6.98

1 study

High PCA-derived retinal reflectance score with GC-IPL thinning is associated with prevalent dementia in humans (OR 6.98).
“Coexisting high PCA-derived scores and GC-IPL thinning further had higher odds of prevalent dementia in combined regions (OR, 3.87) and inferotemporal region (OR, 6.98).”
Humanscoexisting high PCA-derived retinal reflectance score and GC-IPL thinninginferotemporal retinan = 857
Less reflected light in the eye linked to dementia in older adults
Scientific reportsOct 16, 2026

More on High PCA-derived retinal reflectance score with GC-IPL thinning

PCA-derived retinal reflectance score

upin humans1OR 2.21

1 study

PCA-derived retinal reflectance score is associated with prevalent dementia in humans (OR 2.21, 95% CI 1.46–3.35).
“Higher PCA-derived scores were significantly associated with higher odds of prevalent dementia in all regions, strongest in inferotemporal region”
HumansJapanese community residentsinferotemporal retinan = 857
Less reflected light in the eye linked to dementia in older adults
Scientific reportsOct 16, 2026

More on PCA-derived retinal reflectance score

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Scientific Reports5 h

Less reflected light in the eye linked to dementia in older adults

Higher scores indicating less reflected light were associated with 2.21 times the odds of existing dementia in one retinal region.Higher scores indicating less reflected light were associated with 2.21 times the odds of existing dementia in one retinal region.

Cross-sectional · 857 peopleDementia

Paper

Journal of Alzheimer's DiseaseYesterday

High blood pressure linked to contrasting dementia risks in men

Relative risk measures were 0.72 for Alzheimer’s and 1.95 for vascular dementia, comparing systolic pressures of at least 160 versus 120 to below 140 millimetres of…Relative risk measures were 0.72 for Alzheimer’s and 1.95 for vascular dementia, comparing systolic pressures of at least 160 versus 120 to below 140 millimetres of mercury.

Cohort · 2,649 peopleVascular dementia

Paper

Alzheimer Disease and Associated DisordersAug 27