PCA-derived retinal reflectance score

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Prevalent dementia

upin humans1OR 2.21

1 study
  1. PCA-derived retinal reflectance score is associated with prevalent dementia in humans (OR 2.21, 95% CI 1.46–3.35).

    “Higher PCA-derived scores were significantly associated with higher odds of prevalent dementia in all regions, strongest in inferotemporal region”

    HumansJapanese community residentsinferotemporal retinan = 857

    Less reflected light in the eye linked to dementia in older adults

    Scientific reportsOct 16, 2026

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Scientific Reports

Less reflected light in the eye linked to dementia in older adults

Higher scores indicating less reflected light were associated with 2.21 times the odds of existing dementia in one retinal region.Higher scores indicating less reflected light were associated with 2.21 times the odds of existing dementia in one retinal region.

Cross-sectional · 857 peopleDementia