OP-OA comorbidity

Cell fate plasticity is associated with OP-OA comorbidity.

“microenvironment-driven cell fate plasticity may serve as a key mechanistic hub promoting the initiation and progression of OP-OA comorbidity”

Reviewin OP-OA comorbiditysubchondral bone

Mechanistic Links Underlying the Comorbidity of Osteoporosis and Osteoarthritis: Cell Fate Plasticity Driven by the Subchondral Bone Microenvironment

International journal of molecular sciences·25 Jun 2026