Nigrostriatal neurodegeneration

There is 1 paper on nigrostriatal neurodegeneration in aging research: none in people yet, 1 in animals.

1 paper studies it3 more mention it1 finding

See all 4 papers on nigrostriatal neurodegeneration

Animals1

Upstream

1

PINK1

no changein mice1

1 study

PINK1 showed no clear effect on nigrostriatal neurodegeneration in mice (shown by knockout in aged mice).
“nigrostriatal neurodegeneration were not present in aged PINK1-deficient mice”
Animalsshown by knockout in aged micenigrostriatal projection
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
PloS oneJun 3, 2009

Latest

1 paper in 12 months

PLOS OneJun 3

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

Experiments in miceOxidative phosphorylation

NPJ Parkinson's DiseaseDec 13

Long-term oral glucocerebrosidase activator reduces soluble α-synuclein oligomer accumulation in Parkinsonian LRRK2 mutant mouse brain

Experiments in animalsInterventions

Toxicology and Applied PharmacologyAug 2

Oral ingestion of the environmental toxicant trichloroethylene in rats induces alterations in the gut microbiome: Relevance to idiopathic Parkinson's disease

Experiments in ratsMicrobiome composition

PharmaceuticalsSep 6

CCL-11 or Eotaxin-1: An Immune Marker for Ageing and Accelerated Ageing in Neuro-Psychiatric Disorders

ReviewMechanisms