Mild behavioural impairment

Mild behavioural impairment impairs cognitive function in humans (p <0.001; visuospatial p <0.05).

“Individuals with both MBI and Frailty demonstrated the poorest cognitive performance across all domains ( p <0.001) except visuospatial ( p <0.05).”

Humanscross-classified MBI/frailty groups

Double Burden of Mild Behavioural Impairment and Frailty – Implications for Quality of Life and Cognition in a Southeast Asian Cohort

AAIC 2025 abstract·23 Dec 2025

Mild behavioural impairment decreases quality of life in humans (β=-6.2, p <0.001).

“Higher MBI‐C Score correlated with poorer DEMQoL (β=‐6.2; p <0.001).”

Humanscontrolling for age, gender, ethnicity, education, ApoE4 status, marital status, employment, hypertension, hyperlipidaemia, diabetes, and cognitive status

Double Burden of Mild Behavioural Impairment and Frailty – Implications for Quality of Life and Cognition in a Southeast Asian Cohort

AAIC 2025 abstract·23 Dec 2025

Mild behavioural impairment is associated with functional impairment in humans (CR = 2.64; 95%CI: 2.36-2.95).

“MBI+ status (CR = 2.64; 95%CI: 2.36-2.95) were associated with greater global and domain-specific functional impairments.”

Humanscognitively unimpairedn = 1,714

Mild Behavioural Impairment and Everyday Functioning in Cognitively Unimpaired Older Adults: Evidence From the CAN-PROTECT Study

Journal of geriatric psychiatry and neurology·14 Jun 2026