Malignant progression

Papers on malignant progression

43 papers3 new in 30 days

Thursday, October 3

Cell Reports MedicineOct 3

Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma

Experiments in miceLeucine

Monday, April 8

bioRxivApr 8

Mesenchymal Stromal Cell Senescence Induced by Dnmt3a -Mutant Hematopoietic Cells is a Targetable Mechanism Driving Clonal Hematopoiesis and Initiation of Hematologic Malignancy

Preprint: experiments in miceCellular senescence

Monday, March 11

Signal Transduction and Targeted TherapyMar 11

Effects of dietary intervention on human diseases: molecular mechanisms and therapeutic potential

ReviewDietary interventions

Wednesday, November 29

Blood AdvancesNov 29

Genomic landscape of patients with germline RUNX1 variants and familial platelet disorder with myeloid malignancy

Cohort study of 51 peopleMechanisms

Tuesday, October 31

Breast Cancer ResearchOct 31

mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers

Non-randomized trial in peoplemTOR inhibitors

Saturday, June 3

Cancer CellJun 3

Senescent macrophages: A new "old" player in lung cancer development

CommentaryCellular senescence

Thursday, June 2

NatureJun 2

The longitudinal dynamics and natural history of clonal haematopoiesis

Cohort study of 385 peopleBlood and immune system

Tuesday, October 19

American Journal of Cancer ResearchOct 19

Induction of cellular senescence in fibroblasts through β1-integrin activation by tenascin-C-derived peptide and its protumor effect

Experiments in human cellsIntegrin signaling

Wednesday, September 29

BiomedicinesSep 29

Cisd2 Preserves the Youthful Pattern of the Liver Proteome during Natural Aging of Mice

Experiments in miceMechanisms

Thursday, August 6

CancersAug 6

Senescence and Cancer: A Review of Clinical Implications of Senescence and Senotherapies

ReviewCancer

Saturday, May 6

Cell Communication and SignalingMay 6

Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line

Experiments in human cellsIL-6 signaling

Thursday, March 16

Cold Spring Harbor Perspectives in MedicineMar 16

Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres

ReviewTelomerase and telomere maintenance

Wednesday, August 24

Assay and Drug Development TechnologiesAug 24

Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence

Experiments in human cellsImaging