Low-grade and high-grade cervical squamous-cell intraepithelial lesions

HPV types 33/35/52/58 is associated with low-grade and high-grade cervical squamous-cell intraepithelial lesions in humans (Associated with most confirmed lesions).

“most of the cytologically and/or histologically confirmed low-grade and high-grade SILs were associated with non-vaccine-targeted, medium oncogenicity HPV types 33/35/52/58 belonging to clade A9.”

HumansWomen previously vaccinated against HPV types 16/18cervix16-year follow-upfemales

Controlled Trial of Cervical Cancer Screening Frequency Among Human Papillomavirus Vaccinated Women II: Cervical Pre-Cancer End-Points by Specific Non-Vaccine HPV Types

International journal of cancer·15 Oct 2026