Indolent systemic mastocytosis

1. Indolent systemic mastocytosis increases SASP index in humans (2- to 3-fold; M = 3611.6 vs 1355.2).

   “ISM patients had 2- to 3-fold greater SASP index scores (M = 3611.6) compared to HCs (M = 1,355.2; t(39.56)= -7.27, p < 0.001).”

   Humans

   A Senescence Associated Secretory Phenotype (SASP) in Indolent Systemic Mastocytosis Compared to Healthy Controls

   GSA 2025 abstract·31 Dec 2025

More on SASP index