Incident prediabetes or type 2 diabetes

1. Insulin Resistance Risk Score predicts incident prediabetes or type 2 diabetes in humans.

   “IRRS elevation was observed up to 3 years prior to IEs.”

   Humansnormoglycemia at baseline3 yearsn = 16,333

   Among Those with Normoglycemia (NG), Insulin Resistance Risk Score (IRRS) Elevation Is Observed Up to Three Years prior to Diagnosis of Diabetes (T2D) or Prediabetes (PD)

   ADA Scientific Sessions 2025 abstract·13 Jun 2025

2. Insulin Resistance Risk Score raises the risk of incident prediabetes or type 2 diabetes in humans (P <0.001).

   “IE increased across the entire range of IRRS”

   Humansnormoglycemia at baseline3 yearsn = 16,333

   Among Those with Normoglycemia (NG), Insulin Resistance Risk Score (IRRS) Elevation Is Observed Up to Three Years prior to Diagnosis of Diabetes (T2D) or Prediabetes (PD)

   ADA Scientific Sessions 2025 abstract·13 Jun 2025

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