Incident hematologic malignancy

1. Passenger mutation burden is associated with incident hematologic malignancy in humans.

   “passenger burden strongly associated with incident hematologic malignancy and mortality”

   Humansbloodn = 791,067

   Multi-ancestry analysis of 791K whole genomes reveals the genetic, geographic, and phenotypic correlates of somatic passenger mutations in blood

   medRxiv·25 Aug 2026Preprint

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