Incident CVD

Disease1 paper1 finding

  • Humans1

Associations

1

Free androgen index

upin humans1HR 1.41

1 study
  1. Free androgen index raises the risk of incident CVD in humans (HR=1.41, p=0.02).

    Humanspremenopausalfemalesn = 980

    Sex- and Menopause-Specific Hormone-Related ECG Signatures and Incident Cardiovascular Risk in UK Biobank · medRxiv · 17 Sep 2026 · Preprint

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Journal of Translational AutoimmunityHumans

Thyroid antibodies linked to heart risk in younger adults

Across 4,825 adults followed for 14.8 years on average, thyroid antibodies were linked to cardiovascular risk in participants under 40 but not in…Across 4,825 adults followed for 14.8 years on average, thyroid antibodies were linked to cardiovascular risk in participants under 40 but not in those aged 40 and older.

The Journal of Clinical Endocrinology and MetabolismHumans

Hypothalamic amenorrhea in mid-adulthood linked to heart disease

Mid-adulthood functional hypothalamic amenorrhea was linked to a 62% higher cardiovascular disease risk and an HR of 1.91 for coronary heart disease…Mid-adulthood functional hypothalamic amenorrhea was linked to a 62% higher cardiovascular disease risk and an HR of 1.91 for coronary heart disease compared to regular cycles.

Frontiers in Public HealthHumans

High HbA1c-to-HDL-C ratio linked to CVD risk in older adults

Older adults in the highest ratio quartile had a higher risk of incident cardiovascular disease than those in the lowest (HR = 2.111) over five years.Older adults in the highest ratio quartile had a higher risk of incident cardiovascular disease than those in the lowest (HR = 2.111) over five years.

JACC AdvancesHumans

Body fat and inflammation link ultraprocessed food to heart risk

In 6,531 adults, waist-to-height ratio mediated 44% and interleukin-6 mediated 13% of the association between ultraprocessed food intake and incident…In 6,531 adults, waist-to-height ratio mediated 44% and interleukin-6 mediated 13% of the association between ultraprocessed food intake and incident cardiovascular disease.

Journal of Diabetes and Metabolic DisordersHumans

Cumulative non-HDL cholesterol is linked to CVD risk

Each 100-unit increase in cumulative exposure was associated with an adjusted hazard ratio of 1.07 for cardiovascular disease over nine years, driven…Each 100-unit increase in cumulative exposure was associated with an adjusted hazard ratio of 1.07 for cardiovascular disease over nine years, driven by earlier stages.