2 papers1 finding
Sarcopenia
mediatesin humans1
Sarcopenia mediates IADL disability in humans (β=-0.6256, p < 0.0001).
“Similar mediation effects were observed in the relationship between frailty and IADL disability (β=-0.6256, p < 0.0001)”
Humanscommunity-dwelling older adultsn = 571
GSA 2025 abstract31 Dec 2025
In 5,834 community-dwelling older Americans, intrinsic capacity scores showed progressive age-related decline and were lower in females than in males.In 5,834 community-dwelling older Americans, intrinsic capacity scores showed progressive age-related decline and were lower in females than in males.
After accounting for demographic and social factors and multiple illnesses, death-risk ranking scores were 0.723 for brief screening, 0.731 for comprehensive assessment…After accounting for demographic and social factors and multiple illnesses, death-risk ranking scores were 0.723 for brief screening, 0.731 for comprehensive assessment and 0.736 for statistical scoring.
In a longitudinal study of 16,780 older adults over eight years, cardiometabolic multimorbidity and depression together were tied to steeper rises in daily living…In a longitudinal study of 16,780 older adults over eight years, cardiometabolic multimorbidity and depression together were tied to steeper rises in daily living disability.
In three cohorts, hobby engagement was linked to lower ADL disability risk, with hazard ratios of 0.77 in China, 0.73 in Europe, and 0.82 in Mexico.In three cohorts, hobby engagement was linked to lower ADL disability risk, with hazard ratios of 0.77 in China, 0.73 in Europe, and 0.82 in Mexico.