Human immunodeficiency virus type 1 infection

1. Human immunodeficiency virus type 1 infection inhibits DNA repair in humans.

   “This integration often results in unrepaired DNA damage due to the HIV-1-induced inhibition of DNA repair pathways.”

   Review

   The Complex Interactions Between HIV-1 and Human Host Cell Genome: From Molecular Mechanisms to Clinical Practice

   International journal of molecular sciences·29 Mar 2025

More on DNA repair

1. Human immunodeficiency virus type 1 infection activates DNA damage response in humans.

   “HIV-1 proteins can induce DNA damage, block DNA replication, and activate DNA damage responses across various organs.”

   Review

   The Complex Interactions Between HIV-1 and Human Host Cell Genome: From Molecular Mechanisms to Clinical Practice

   International journal of molecular sciences·29 Mar 2025

More on DNA damage response

1. Human immunodeficiency virus type 1 infection inhibits telomerase and telomere maintenance in humans.

   “Furthermore, HIV-1 infection causes telomere attrition in host chromosomes”

   Review

   The Complex Interactions Between HIV-1 and Human Host Cell Genome: From Molecular Mechanisms to Clinical Practice

   International journal of molecular sciences·29 Mar 2025

More on Telomerase and telomere maintenance