Glucolipotoxicity

Papers on glucolipotoxicity

15 papers2 new in 30 days

Saturday, November 7

Chemical Engineering JournalNov 7

Nanotherapy rejuvenating mitochondria via SIRT1 ubiquitination suppression attenuates glucolipotoxicity and promotes diabetic bone regeneration

Figure from Chemical Engineering Journal

Experiments in animalsBones and joints

Friday, October 30

Lipids in Health and DiseaseOct 30

Sex-dimorphic phenotypic divergence in metabolically driven thyroid nodules: the interplay of systemic inflammation and adiposity

Screening flowchart. Abbreviations: TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; FPG: fasting plasma glucose; RDW: red blood cell distribution width

Cross-sectional study of 24,878 peopleBiomarkers

Tuesday, October 6

Frontiers in Cell and Developmental BiologyOct 6

Cellular senescence of renal tubular epithelial cells in diabetic kidney disease: emerging mechanisms and targeted interventions

Stimuli induce cellular senescence Figure Caption:DNA damage, paracrine propagation of senescence, metabolic dysregulation, oxidative stress, epigenetic regulation, and compromised endogenous…

ReviewCellular senescence

Tuesday, August 4

EndocrinologyAug 4

Physical activity and human islet amyloid polypeptide islet amyloidosis: mechanistic plausibility, missing evidence, and future directions

ReviewMechanisms

Monday, August 3

Molecular and Cellular BiochemistryAug 3

Liraglutide affects mitochondrial function and histone acetylation through the NQO1/SIRT3 pathway in diabetic kidney disease

Experiments in ratsLiraglutide

Wednesday, June 3

Frontiers in Clinical Diabetes and HealthcareJun 3

Pathogenesis of diabetic cardiomyopathy and emerging therapeutic strategies: a network-based perspective

ReviewMechanisms

Friday, February 27

AntioxidantsFeb 27

Plasma EV miR-186-5p as an Early Biomarker and Regulator of IFN-α-Mediated Oxidative and β-Cell Dysfunction in Prediabetes

Cohort study of 150 peoplePrediabetes

Monday, November 18

Free Radical Biology & MedicineNov 18

AQP1 mediates pancreatic β cell senescence induced by metabolic stress through modulating intracellular H₂O₂ level

Experiments in mouse cellsCellular senescence

Tuesday, September 17

Advances in Experimental Medicine and BiologySep 17

Mechanism of Obesity-Related Lipotoxicity and Clinical Perspective

ReviewMechanisms

Wednesday, September 8

PhytomedicineSep 8

Urolithin A suppresses glucolipotoxicity-induced ER stress and TXNIP/NLRP3/IL-1β inflammation signal in pancreatic β cells by regulating AMPK and autophagy

Experiments in miceUrolithin A

Friday, May 7

Nutrition & MetabolismMay 7

Protective effects of calorie restriction on insulin resistance and islet function in STZ-induced type 2 diabetes rats

Experiments in 60 ratsDietary restriction

Tuesday, November 24

Journal of EthnopharmacologyNov 24

Urolithin A, a pomegranate metabolite, protects pancreatic β cells from apoptosis by activating autophagy

Experiments in miceUrolithin A

Sunday, September 15

The American Journal of MedicineSep 15

Strategies of Unloading the Failing Heart from Metabolic Stress

ReviewInterventions

Wednesday, January 20

International Journal of Molecular SciencesJan 20

Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53

Experiments in miceMetformin

Thursday, January 7

The FEBS JournalJan 7

Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity

Experiments in rat cellsInterventions