Esophageal cancer risk

There is 1 paper on esophageal cancer risk in aging research: 1 observational study in people. The newest story, Oct 27, 2026: “Combinations of gene variants linked to four cancer types”.

Disease

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“Among MMR PGV carriers, rs671 GA/AA was associated with increased risk of esophageal and colorectal cancers (odds ratio, 95.62 and 24.57, respectively)”
Joint Effects of ALDH2 rs671 and Pathogenic Germline Variants in DNA Repair Genes on Risk of Aerodigestive and Gastrointestinal CancersCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2026doi:10.1158/1055-9965.epi-26-0629
  • Humans1

Associations

1

ALDH2RS671GA/AA

upin humans1

1 study
  1. ALDH2RS671GA/AA is associated with esophageal cancer risk in humans (MMR pathogenic germline variant carriers) (OR 95.62; interaction P = 0.017).

    “Among MMR PGV carriers, rs671 GA/AA was associated with increased risk of esophageal and colorectal cancers (odds ratio, 95.62 and 24.57, respectively)”

    HumansMMR pathogenic germline variant carriers

    Combinations of gene variants linked to four cancer types

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

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Cancer Epidemiology, Biomarkers & Prevention

Combinations of gene variants linked to four cancer types

The case-control study compared 4,418 people with cancer and 11,811 controls, finding links that differed by cancer site and alcohol intake.The case-control study compared 4,418 people with cancer and 11,811 controls, finding links that differed by cancer site and alcohol intake.

Case-control studyPopulations