Endometriosis or adenomyosis

1. Endometriosis or adenomyosis has no effect on epigenetic age acceleration using other established clocks in humans (Z-score mean differences ranged from -0.10 to 0.06).

   “No notable differences were observed in the estimates of epigenetic age acceleration using the other established clocks”

   HumansDuring pregnancy; endometriosis or adenomyosis versus neither conditionperipheral bloodfemales

   Differences in epigenetic age acceleration according to a diagnosis of endometriosis/adenomyosis: the Norwegian Mother, Father and Child Cohort Study

   American journal of obstetrics and gynecology·30 Mar 2026

More on Epigenetic age acceleration using other established clocks

1. Endometriosis or adenomyosis has no effect on Horvath pan-tissue clock epigenetic age acceleration in humans (Adjusted z-score mean difference 0.00; 95% CI -0.13 to 0.13).

   “After multivariable adjustment, the significant difference in the Horvath pan-tissue clock was attenuated (mean difference in the z-score, 0.00; 95% confidence interval, -0.13 to 0.13).”

   HumansDuring pregnancy; endometriosis or adenomyosis versus neither condition, after multivariable adjustmentperipheral bloodfemales

   Differences in epigenetic age acceleration according to a diagnosis of endometriosis/adenomyosis: the Norwegian Mother, Father and Child Cohort Study

   American journal of obstetrics and gynecology·30 Mar 2026

More on Horvath pan-tissue clock epigenetic age acceleration