Horvath pan-tissue clock epigenetic age acceleration

1. Endometriosis or adenomyosis has no effect on Horvath pan-tissue clock epigenetic age acceleration in humans (Adjusted z-score mean difference 0.00; 95% CI -0.13 to 0.13).

   “After multivariable adjustment, the significant difference in the Horvath pan-tissue clock was attenuated (mean difference in the z-score, 0.00; 95% confidence interval, -0.13 to 0.13).”

   HumansDuring pregnancy; endometriosis or adenomyosis versus neither condition, after multivariable adjustmentperipheral bloodfemales

   Differences in epigenetic age acceleration according to a diagnosis of endometriosis/adenomyosis: the Norwegian Mother, Father and Child Cohort Study

   American journal of obstetrics and gynecology·30 Mar 2026

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