Drug dependence
1 paper1 finding
- Humans1
Associations
1Mitochondrial DNA copy number
downin humans1
1 study
Mitochondrial DNA copy number
downin humans1
Drug dependence is associated with mitochondrial DNA copy number in humans.
“Sex-associated analysis revealed a significant mtDNAcn reduction in the DD males”
Humansdrug dependencemales
Biochemical geneticsNov 30, 2024
Trial sponsors
2 trialsPhase 2/3157 people
Latest
2 in 12 monthsStem Cell Research & Therapy
Endothelial progenitor cell susceptibility to DNA damaging and DDR-modulating compounds determines endothelial differentiation accuracy
Experiments in mouse cellsMechanisms
Frontiers in Immunology
Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach
Experiments in miceMultiple sclerosis
Biochemical Genetics
Altered Mitochondrial DNA Copy Number and Telomere Length in Patients with Substance Use Disorder: Correlation with Age, Sex, and Chronic Diseases
Cross-sectional study of 54 peopleMitochondrial DNA copy number
The Lancet Healthy Longevity
Preparedness for healthy ageing and polysubstance use in long-term cannabis users: a population-representative longitudinal study
Cohort study of 938 peoplePopulations
Biological Psychiatry Cognitive Neuroscience and Neuroimaging
Accelerated and Premature Aging Characterizing Regional Cortical Volume Loss in Human Immunodeficiency Virus Infection: Contributions From Alcohol, Substance Use, and Hepatitis C Coinfection
Cohort study of 549 peopleHIV infection
JAMA Psychiatry
The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise
Study in peoplePopulations