Dementia and cognitive impairment

Disease

1 paper studies it115 more mention it2 findings

Associations

2

HIV infection

upin humans1RR 2.07

1 study
  1. HIV infection is associated with dementia and cognitive impairment in humans (RR 2.07, 95% CI 1.35–3.17).

    “HIV infection was significantly associated with an increased risk of dementia and cognitive impairment (RR=2.07, 95% CI: 1.35, 3.17).”

    Review

    Association of HIV infection with dementia and cognitive impairment: A systematic review and meta-analysis

    Journal of Alzheimer's disease reports

More on HIV infection

Total healthcare costs

upin humans1

1 study
  1. Dementia and cognitive impairment is associated with total healthcare costs in humans (+$6883).

    “those with cohort-based DCI vs. no DCI had higher incremental THC ($6883 in women and $7276 in men).”

    Humansadjusted for age, race, geographic region, and multimorbidity36 monthsfemalesn = 8,165

    EFFECTS OF FRAILTY AND FUNCTIONAL IMPAIRMENT ON THE ASSOCIATIONS OF COGNITIVE IMPAIRMENT AND DEMENTIA WITH HEALTHCARE COSTS

    GSA 2024 abstract

Funding

2 grants since 2016

UK Research and Innovation£863.8kNational Health and Medical Research CouncilA$513.1k

Latest

Nov 2025: 2Dec 2025: 11Jan 2026: 4Feb 2026: 3Mar 2026: 1Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 1Aug 2026: 4Sep 2026: 3Oct 2026: 333 papers in 12 months
Scientific Reports

A protein mutation curbs brain damage in mice with dementia

Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.

Experiments in miceMechanisms
AJNR American Journal of Neuroradiology

Carotid stenting linked to more cognitive decline than surgery

In asymptomatic carotid stenosis, five-year rates of cognitive decline or dementia were 18.06% after carotid stenting versus 15.24% after carotid endarterectomy.In asymptomatic carotid stenosis, five-year rates of cognitive decline or dementia were 18.06% after carotid stenting versus 15.24% after carotid endarterectomy.

Cohort study of 4,822 peopleInterventions