Deep vein thrombosis

Disease7 papers7 findings

  • Human trial1
  • Humans6

Upstream

2

Body mass index

mediatesin humans1

1 study
  1. Body mass index mediates deep vein thrombosis in humans (7.58% - 10.50% of ALM-DVT, 52.74% - 62.73% of LFM-DVT).

    Humansmediates ALM-DVT and LFM-DVT effect

    Genetically Predicted Muscle Mass and Function in Relation to Deep Vein Thrombosis: A Two-step Mendelian Randomization Study Highlighting the Mediating Role of BMI · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 10 Sep 2026

Body mass index →

Grip strength

no changein humans1

1 study
  1. Grip strength has no effect on deep vein thrombosis in humans.

    Humans

    Genetically Predicted Muscle Mass and Function in Relation to Deep Vein Thrombosis: A Two-step Mendelian Randomization Study Highlighting the Mediating Role of BMI · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 10 Sep 2026

Grip strength →

Associations

4

GLP-1 receptor agonists

downin humans2HR 0.642Low certainty

2 studies
  1. GLP-1 receptor agonists lower the risk of deep vein thrombosis in humans (HR 0.642, 95% CI 0.586-0.702).

    Humanspatients with type 2 diabetes and inflammatory bowel diseasen = 32,236

    Cardiovascular outcomes associated With GLP-1 and dual GLP-1/GIP receptor agonists in patients with type 2 diabetes and inflammatory bowel disease: A retrospective real-world cohort study · PloS one · 24 Sep 2026

  2. GLP-1 receptor agonists lower the risk of deep vein thrombosis in humans (RR 0.53, 95% CI 0.31-0.89).

    Humans90-day

    Preoperative GLP-1 receptor agonist use and outcomes after total hip arthroplasty: a matched cohort study · Hip international : the journal of clinical and experimental research on hip pathology and therapy · 11 Sep 2026

GLP-1 receptor agonists →

Leg fat-free mass

upin humans1OR 1.92–1.954

1 study
  1. Leg fat-free mass raises the risk of deep vein thrombosis in humans (OR = 1.920-1.954).

    Humans

    Genetically Predicted Muscle Mass and Function in Relation to Deep Vein Thrombosis: A Two-step Mendelian Randomization Study Highlighting the Mediating Role of BMI · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 10 Sep 2026

Leg fat-free mass →

Appendicular lean mass

upin humans1OR 1.288

1 study
  1. Appendicular lean mass raises the risk of deep vein thrombosis in humans (OR 1.288, 95% CI 1.215-1.365).

    Humansin FinnGen

    Genetically Predicted Muscle Mass and Function in Relation to Deep Vein Thrombosis: A Two-step Mendelian Randomization Study Highlighting the Mediating Role of BMI · Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 10 Sep 2026

Appendicular lean mass →

Exercise

downin humans1Low certainty

1 study
  1. Exercise lowers the risk of deep vein thrombosis in humans.

    Humans

    Association between preoperative physical exercise and the risk of postoperative venous thromboembolism: nationwide population-based cohort study · BJS open · 4 Sep 2026

Exercise →

Trial sponsors

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