Cytomegalovirus reactivation

1. CD28lo KLRG1hi IL-7Rlo HLA-DRhi CD8+ T cells lower the risk of cytomegalovirus reactivation in humans (p =0.0163).

   “CD28lo KLRG1hi IL-7R (CD127)lo HLA-DRhi CD8+ T cells present prior to the detection of viremia in CMV-seropositive patients emerged as a key feature distinguishing patients who did or did not undergo CMV reactivation”

   Humansin CMV-seropositive kidney transplant recipients prior to viremia detection

   Cytotoxic KLRG1+ IL-7R- effector CD8+ T cells distinguish kidney transplant recipients controlling cytomegalovirus reactivation

   Frontiers in immunology·Feb 14, 2025

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