Coronary heart disease events

1. Impaired glucose tolerance has no effect on coronary heart disease events in humans.

   “the incidence of CHD events was not significantly different among groups, perhaps owing to the limited number of events.”

   Humans9.5 yearsn = 937

   Impaired glucose tolerance, but not impaired fasting glucose, is associated with increased levels of coronary heart disease risk factors: results from the Baltimore Longitudinal Study on Aging

   Diabetes·1 Aug 2004

1. Duration of diabetes predicts coronary heart disease events in humans.

   “duration of diabetes (P < 0.05) predicted CHD death (n = 15) and all CHD events (n = 33).”

   HumansType 2 diabetes3.5 yearsn = 229

   NIDDM and its metabolic control predict coronary heart disease in elderly subjects

   Diabetes·1 Aug 1994

1. HbA1c predicts coronary heart disease events in humans (OR 2.2, 95% CI 1.0–5.1).

   “CHD death and all CHD events in NIDDM subjects with GHbA1c levels higher than 7.0% compared with diabetic subjects with lower GHbA1c (ORs 4.3 [1.1-16.7] and 2.2 [1.0-5.1]).”

   HumansType 2 diabetes; baseline HbA1c higher than 7.0% versus lower HbA1c3.5 yearsn = 229

   NIDDM and its metabolic control predict coronary heart disease in elderly subjects

   Diabetes·1 Aug 1994

More on HbA1c

1. Type 2 diabetes predicts coronary heart disease events in humans (CHD death or nonfatal MI: 14.8% in NIDDM subjects versus 3.4% in nondiabetic subjects).

   “During the follow-up, 3.4% of nondiabetic and 14.8% of NIDDM subjects died from CHD or had a nonfatal myocardial infarction (MI).”

   HumansFinnish population sample3.5 yearsn = 1,298

   NIDDM and its metabolic control predict coronary heart disease in elderly subjects

   Diabetes·1 Aug 1994

More on Type 2 diabetes