Cognitive pre-frailty

Disease

2 papers1 finding

  • Humans1
  • Animals1

Upstream

1

NLRP3

downin mice1

1 study
  1. NLRP3 decreases cognitive pre-frailty in mice.

    “Nlrp3 deletion markedly attenuated age-associated behavioral decline, resulting in preserved locomotor activity, learning, and memory and a substantially reduced prevalence of cognitive pre-frailty in middle-aged mice.”

    AnimalsNlrp3 deletion

    Dual roles of basal NLRP3 expression in cognitive and neurogenic aging

    Biogerontology4 Mar 2026

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