Cholestatic fibrosis

1 paper studies it1 finding

Animals1

Upstream

1

MSLN

upin mice1

1 study

MSLN increases cholestatic fibrosis in mice.
“Deletion of Msln or Muc16 ameliorated cholestatic fibrosis, inflammation and HCC in Mdr2-/-Msln-/- and Mdr2-/-Muc16-/- mice”
Animalsin Mdr2-/- miceliver
Mesothelin/Mucin 16 Signaling in Activated Portal Fibroblasts Drives the Development of Cholestatic Fibrosis and Hepatocellular Carcinoma in Aged Female Multidrug Resistance Protein 2 Knockout Mice
Cellular and molecular gastroenterology and hepatologyApr 11, 2026

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Cellular and Molecular Gastroenterology and HepatologyApr 13

Mesothelin/Mucin 16 Signaling in Activated Portal Fibroblasts Drives the Development of Cholestatic Fibrosis and Hepatocellular Carcinoma in Aged Female Multidrug Resistance Protein 2 Knockout Mice

Experiments in micep38 MAPK signaling