Central Lewy body diseases

1. Central Lewy body diseases impair cellular homeostasis in humans.

   “LBDs feature a vesicular storage defect in extant catecholaminergic terminals, exemplifying the "sick-but-not-dead" phenomenon.”

   Reviewin LBDs

   Preclinical Catecholaminergic Biomarkers of Central Lewy Body Diseases

   Journal of clinical neurology (Seoul, Korea)·1 Jan 2026

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1. 18F-dopamine PET predicts central Lewy body diseases in humans.

   “Central LBDs can begin outside the brain ("body-first"), with early involvement of cardiac sympathetic nerves as evidenced by 18F-dopamine positron emission tomography (PET)”

   Reviewin at-risk individuals

   Preclinical Catecholaminergic Biomarkers of Central Lewy Body Diseases

   Journal of clinical neurology (Seoul, Korea)·1 Jan 2026

More on 18F-dopamine PET