Carotid atherosclerotic plaques

Disease

1 paper3 findings

  • Humans1

Associations

3

C-reactive protein

upin humans1

1 study
  1. C-reactive protein predicts carotid atherosclerotic plaques in humans.

    “Fibrinogen and CRP performed well, but with lesser significance, as predictors of the presence of carotid plaques (p = 0.002).”

    HumansHospitalized patientscarotid arteryn = 324

    Neutrophil-to-Lymphocyte Ratio is a strong predictor of atherosclerotic carotid plaques in older adults

    Nutrition, metabolism, and cardiovascular diseases : NMCD5 Nov 2017

More on C-reactive protein

Fibrinogen

upin humans1

1 study
  1. Fibrinogen predicts carotid atherosclerotic plaques in humans.

    “Fibrinogen and CRP performed well, but with lesser significance, as predictors of the presence of carotid plaques (p = 0.002).”

    HumansHospitalized patientscarotid arteryn = 324

    Neutrophil-to-Lymphocyte Ratio is a strong predictor of atherosclerotic carotid plaques in older adults

    Nutrition, metabolism, and cardiovascular diseases : NMCD5 Nov 2017

More on Fibrinogen

Neutrophil-to-lymphocyte ratio

upin humans1

1 study
  1. Neutrophil-to-lymphocyte ratio predicts carotid atherosclerotic plaques in humans (80% probability at NLR >2.4; 97% probability at NLR >3.68).

    “NLR > 2.4 predicted with 80% probability carotid plaques (p < 0.01), while NLR > 3.68 gave 97% probability (p = 0.013).”

    HumansHospitalized patients; NLR thresholds >2.4 and >3.68carotid arteryn = 324

    Neutrophil-to-Lymphocyte Ratio is a strong predictor of atherosclerotic carotid plaques in older adults

    Nutrition, metabolism, and cardiovascular diseases : NMCD5 Nov 2017

More on Neutrophil-to-lymphocyte ratio

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International Immunopharmacology

Rapamycin improves efferocytosis and reduces plaques in mice

In ApoE-/- mice, rapamycin reduced aortic lipid-positive area from 25.32 ± 0.98% to 12.28 ± 1.49% and increased plaque efferocytosis index from 0.36 ± 0.02 to 1.37 ±…In ApoE-/- mice, rapamycin reduced aortic lipid-positive area from 25.32 ± 0.98% to 12.28 ± 1.49% and increased plaque efferocytosis index from 0.36 ± 0.02 to 1.37 ± 0.15.

Experiments in miceRapamycin