Cardiovascular disease and hypertension

1. Cardiovascular disease and hypertension is associated with whole-blood NAD+ in humans.

   “but are reduced in chronic diseases, specifically cardiovascular disease and hypertension.”

   Humanswhole blood

   Lower whole-blood NAD linked to high blood pressure

   Nature metabolism·Nov 4, 2026

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1. Alcohol is linked with a higher risk of cardiovascular disease and hypertension in humans with parental financial difficulty compared to peers without (9.7 percentage points (95% CI: 0.8-18.5)).

   “Alcohol use alone exhibited a differential effect of 9.7 percentage points (95% CI: 0.8-18.5).”

   Humanswith parental financial difficulty compared to peers without21 yearsn = 4,452

   Unequal effects of health behaviors in adolescence on adult cardiovascular disease and hypertension by family financial situation in the US: A cohort study

   medRxiv·Mar 12, 2026Preprint

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1. Frequent alcohol use and concurrent cigarette smoking is linked with a higher risk of cardiovascular disease and hypertension in humans with parental financial difficulty compared to peers without (11.1 percentage points (95% CI: 0.1-22.1)).

   “Frequent alcohol use and concurrent cigarette smoking led to 11.1 percentage points more cases (95% CI: 0.1-22.1) among adolescents with parental financial difficulty compared to peers without.”

   Humanswith parental financial difficulty compared to peers without21 yearsn = 4,452

   Unequal effects of health behaviors in adolescence on adult cardiovascular disease and hypertension by family financial situation in the US: A cohort study

   medRxiv·Mar 12, 2026Preprint

More on Frequent alcohol use and concurrent cigarette smoking