Molecular Biomedicine
Higher sirtuin 1 is linked to lower aortic valve disease risk
A genetic analysis supported an inverse association between sirtuin 1 expression and the risk of calcific aortic valve disease.A genetic analysis supported an inverse association between sirtuin 1 expression and the risk of calcific aortic valve disease.
Mendelian randomizationSirtuin signaling
Who was studiedPeople with genetic data
What changedHigher sirtuin 1 expression was linked to lower calcific aortic valve disease risk
The catchSIRT1-raising treatment effects on valve disease in people were not measured